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- *************************************
- * Mannitol dehydrogenases signature *
- *************************************
-
- The following dehydrogenases have been shown [1] to be evolutionary related:
-
- - Mannitol-1-phosphate 5-dehydrogenase (EC 1.1.1.17) (gene mtlD), which
- catalyzes the NAD-dependent reduction of mannitol 1-phosphate into fructose
- 6-phosphate.
- - Mannitol 2-dehydrogenase (EC 1.1.1.67) (gene mtlK), which catalyzes the
- NAD-dependent reduction of mannitol into fructose.
- - Escherichia coli hypothetical protein yeiQ.
-
- As a signature pattern we selected a conserved region located in the central
- section of these enzymes.
-
- -Consensus pattern: F-x(2)-[STAG]-x-V-D-R-I-x-P
- -Sequences known to belong to this class detected by the pattern: ALL.
- -Other sequence(s) detected in SWISS-PROT: NONE.
- -Last update: June 1994 / First entry.
-
- [ 1] Schneider K.-H., Giffhorn F., Kaplan S.
- J. Gen. Microbiol. 139:2475-2484(1993).
-